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News - CoQ10 may reduce muscle damage during intensive exercise

By Nutri People

While moderate exercise is associated with many health benefits, high-level strenuous exercise can lead to muscle problems, increased levels of inflammation and oxidative stress. To try to combat this, scientists from Spain recently conducted a study to find out whether oral coenzyme Q10 (CoQ10) supplementation can prevent the over-expression of inflammatory mediators and increase oxidative stress associated with strenuous exercise.

To carry out the study, participants were classified in two groups. One group received CoQ10 supplements, while the other group were given dummy pills. The first 30mg of CoQ10 was taken two days before the test, then a further three 30mg tablets were taken the following day, with a final 30mg dose being administered half an hour before the physical test began. The physical test consisted of a constant 50km run through mountainous terrain.

Results showed that the group receiving the CoQ10 supplements had much lower levels of oxidative stress compared to the control group as well as improved antioxidant status. What’s more, the data also indicated that the CoQ10 prevented over-expression of the inflammatory marker TNF-α after exercise, as well as decreasing the participants’ creatinine production, suggesting reduced levels of muscle damage. 

Article References

Díaz-Castro J et al. Coenzyme Q(10) supplementation ameliorates inflammatory signaling and oxidative stress associated with strenuous exercise. Eur J Nutr. 2011 Oct 12

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