News - Quercetin May Lower Blood Pressure
Quercetin, a major dietary flavonoid occurs naturally in many plant foods, including onions, broccoli, green cabbage and apples. It is also found in lower concentrations in black tea and red wine. Best known for its antioxidant and allergy curbing effects, quercetin has also demonstrated anti-inflammatory and vasorelaxant properties. These effects have been investigated in a recent trial, which examined the effects of quercetin supplements on risk factors for heart disease, markers of inflammation and oxidative stress levels.
The double-blind crossover study included 49 healthy male subjects who were all genetically at higher risk of heart disease. The subjects were divided into two groups and half were given 150mg of quercetin per day while the other half received dummy pills. After eight weeks, a three week washout period was used before the two groups were swapped over. After each stage of the trial the participants’ blood vessel health, body measurements, metabolic and inflammatory parameters were recorded both in a fasting state and after a fat-rich meal.
The results showed that in all subjects combined, quercetin significantly decreased waist circumference and post-meal systolic blood pressure. Post meal triglyceride concentrations were also significantly decreased and levels of beneficial HDL-cholesterol increased after quercetin as compared to those taking the dummy pills.
Pfeuffer M et al. Effect of quercetin on traits of the metabolic syndrome, endothelial function and inflammatory parameters in men with different APOE isoforms. Nutr Metab Cardiovasc Dis. 2011 Nov 23.