News - Vitamin E Linked To Better Mental Function
The build-up of beta-amyloid plaque is associated with an increase in brain cell damage and death as a result of oxidative stress. This degeneration of the brain, or atrophy, is a common symptom of mild cognitive impairment, and can be an early warning to signs of Alzheimer’s. This has led to interest in antioxidant status and its relationship with long-term cognitive health.
In one new study published in Neurobiology of Aging, researchers have found evidence that people with decreased mental function and Alzheimer’s disease are more likely to have low blood levels of vitamin E compared to people with normal cognitive function.
The European researchers analysed data from 168 Alzheimer patients, 166 people with mild cognitive impairment, and 187 people with normal cognitive function. The data indicated that people with Alzheimer’s disease and mild cognitive impairment had lower blood levels of vitamin E. After crunching the numbers, the researchers calculated that people with both forms of cognitive decline were 85% less likely to have the highest average levels of vitamin E.
Dr Mangialasche and her co-workers added that subjects with Alzheimer’s disease and mild cognitive impairment displayed higher levels of vitamin E damage markers compared to the cognitively normal group of subjects. This result suggested a direct link between oxidative stress in early Alzheimer’s onset and low levels of vitamin E.
Mangialasche et al. “Tocopherols and tocotrienols plasma levels are associated with cognitive impairment” Neurobiology of Aging.