News - Study highlights role of magnesium in type 2 diabetes
According to new research published in Clinical Nutrition, low magnesium status may exacerbate the symptoms of type 2 diabetes by influencing insulin status. The findings suggest that long-term hyperglycaemia and the accompanying excessive excretion of magnesium into the urine can increase the risk of diabetes complications.
The cross-sectional study assessed magnesium intake and status in a group of 51 type 2 diabetics. Magnesium intake was assessed by three 24-hour dietary recalls. Urine, plasma and erythrocyte magnesium, fasting and two-hour postprandial glucose, glycosylated haemoglobin, microalbuminuria, proteinuria and serum and urine creatinine, were also measured.
When the results were analysed, it was found that 77% of participants presented with one or more magnesium status parameters below the cut-off points. In addition, low magnesium status was found to be associated with increased kidney excretion of magnesium and reduced blood sugar control.
In their conclusions, the authors of the study explained that since magnesium is essential for energy production and proper insulin signalling, it is not surprising that deficiency of the mineral is implicated in the impairment of metabolic control. They concluded that impaired kidney function might lead to high levels of magnesium in the urine, which, together with low magnesium intake, can induce a rise in glucose in the blood.
Sales CH et al. Influence of magnesium status and magnesium intake on the blood glucose control in patients with type 2 diabetes. Clinical Nutrition. 2011.